You have probably already read NLAMLAF’s excellent post on vitamin D wrt COVID 19 with George’s excellent comments. That post addressed the clinical efficacy of vitamin D. Physiologically vitamin D works especially well with SARS because it inhibits renin from whence angiotensin II comes. You probably know that I favor the ARB losartan (therapeutic), esp in conjunction with Vitamin D (preventatiby PC, MD - GENERAL HEALTH FORUM
Email me and I'll send you a pdf. Indicate whether you want the whole book or just the addendum.by PC, MD - GENERAL HEALTH FORUM
Just go to B&N (not Amazon) and search the title. "Author" is my two golden retrievers. Let me know if B&N have also removed it, although I doubt it. Look at "Plan B."by PC, MD - GENERAL HEALTH FORUM
Hi Elizabeth, Thanks for the post. It’s always nice to get feedback. As you suggested, universal basic income will be the carrot that opens the flood gates of socialism, paid for by higher taxes generated by a sovereign cryptocurrency, wealth tax, ... I actually wrote under a pseudonym a free ebook (Amazon, Barnes & Noble,…) about this in the middle of 2017 entitled From Freedom to Fby PC, MD - GENERAL HEALTH FORUM
From Apr 17, 2020 Mortality amongst hypertensive COVID inpatients is almost 3 times greater in those not taking ACEIs/ARBs.by PC, MD - GENERAL HEALTH FORUM
Hi George, Thanks for the link. I read the article and it doesn’t do anything more than raise the same questions and is all speculation. Furthermore, it ignores the data we do have without having to wait a year for some clinical trial. How many will die in the meantime? Table 2 on page 29 is actionable real time data. Nobody seems to talk about the actual physiology of AT1R, TACE, and the acby PC, MD - GENERAL HEALTH FORUM
Aloha Mike, Thanks for your post. Unfortunately the link was dead. But no matter. I really don’t care about infectivity but about the inflammation induced. Here in Hawaii everybody hates Trump and embraces global warming. HI is one of the 8 states that went over 60% for Hillary. These same eight states are at the absolute bottom of the 50 in terms of state debt. Trump just officially oby PC, MD - GENERAL HEALTH FORUM
Aloha The Anti Fib, Wouldn't change a thing. Looks like you're good. Always good to remember to do what you can to eliminate comorbidities naturally, e.g., exercise, diet. I get my selenium from Brazil nuts and pumpkin seeds, but that's just me. I only take about 2000 mg Vit C per day, but your strategy looks good. Until I switched to liposomal Vitamin C I got a lot of gas, buby PC, MD - GENERAL HEALTH FORUM
Hi George, Listened to the entire interview. I can see why you like the guy. I too like almost everything he says, but he's mixing up two separate issues: balance and root causes in health v treating an infectious disease. I guess nobody understands the image I keep posting about AT1R blockage and the ACE2 receptor. The virus can't enter the cell if it is still attached toby PC, MD - GENERAL HEALTH FORUM
Hi Liz, I have friends in The Bronx who work at Albert Einstein in a healthcare capacity. They are both in the early 60s and both converted to positive COVID-19. He’s hypertensive And she has osteoporosis. Amazingly neither ever had any symptoms whatsoever after several weeks. Turns out he was on 25 mg of losartan and she gets 50,000 IUs IM of vitamin D per week. This is all anecdotal. Butby PC, MD - GENERAL HEALTH FORUM
Hi hwkmn05, Hydroxychloroquine has gotten rave reviews, but I personally like Losartan. As I've said in my original post, it's not about the virus, it's about the inflammation. Clinicians are beginning to realize that COVID19 is more like high altitude pulmonary edema (HAPE) and ventilators are no good. Oxidative stress is the culprit. Losartan abolishes oxidative streby PC, MD - GENERAL HEALTH FORUM
One final post on this thread from me. The below link succinctly describes what’s happening with angiotensin II and COVID-19 The virus destroys the cells that carry the membrane bound ACE2 receptors, leading to an imbalance in the RAS with more angiotensin II. Increased angiotensin II in diabetics and hypertensives is precisely why these are the top two comorbidities for COVID 19 and sby PC, MD - GENERAL HEALTH FORUM
Hi Jackie, You forgot to mention the recall of losartan et al. for containing carcinogenic substances. Here’s the latest from the FDA on blood pressure meds with a cancer-causing element (Jan, 2019) “If 8,000 people took the highest daily valsartan dose (320 mg) that contained NDMA, for four years (the time we think the affected products had been on the U.S. market), there may be one addby PC, MD - GENERAL HEALTH FORUM
NLAMA I always like to understand exactly how something might work, which means the physiology in this case. This link explains my thinking IMHO the real culprit, the one responsible for the deaths is angiotensin II. Sure the virus destroys the cells that carry the membrane bound ACE2 receptors, leading to an imbalance in the RAS and more angiotensin II. But I'd rather attack tby PC, MD - GENERAL HEALTH FORUM
Certainly agree with your comments NLAMA. But my first priority is to stay out of the hospital. I just received an advance copy of a soon to be published article that has not yet been peer reviewed from a professional Italian colleague. He practices in Milan, ground zero for COVID-19 in Italy, but the article originates in Iran. The English is a little stilted. I eagerly await the UoMinn clby PC, MD - GENERAL HEALTH FORUM
I just received an advance copy of a soon to be published article that has not yet been peer reviewed from a professional Italian colleague. He practices in Milan, ground zero for COVID-19 in Italy, but the article originates in Iran. The English is a little stilted. Inhibition of Viral Macrodomain of COVID-19 and Human TRPM2 by losartan (posted today March 31) Conclusion It seems Losaby PC, MD - GENERAL HEALTH FORUM
NLAMA Your friend (haha) Dr Mercola has lots of good things to say about zinc and quercetain. I think Liz will also be interested. also re Losartan I like George’s approach, although I hesitate at the high doses of Dby PC, MD - GENERAL HEALTH FORUM
NLAMA It’s not all about COVID 19 or SARS CoV or MERS or ..., IMHO It’s all about preventing the excessive inflammatory response, cytokine storm, .. Vitamin C and D do this and not just for COVID 19. They allow you the time to develop natural immunity before you might otherwise succumb. I’m not trying to convince you. You are the captain of your own ship. I’m just trying to throw some more dby PC, MD - GENERAL HEALTH FORUM
Well don’t throw the baby out with the bath water. The overarching point is lots of D and C.by PC, MD - GENERAL HEALTH FORUM
Great video Elizabeth To add to Dr. B’s testimonial, here’s Dr. M’s To answer Dr. B’s patient’s question about why such treatment is not available in the hospital or even mentioned in the lame stream media It’s a rather long video but just listen to the portion after the 30 minute markby PC, MD - GENERAL HEALTH FORUM
Hi NotLyingAboutMyAfib, Your protocol looks good. But it would be even better if you add Vitamins D and Cby PC, MD - GENERAL HEALTH FORUM
Hi Shannon, This thread has very limited relevance to LAF. Please feel free to transfer to the General Forum, if you so chose. Whatever you think. I don't think anyone will care or be offended. My favorite Dr. Seuss quote "Be who you are, say what you think; those that mind don’t matter, and those that matter don’t mind."by PC, MD - GENERAL HEALTH FORUM
Sorry about that Joe This webpage is great for all things Vitamin D.by PC, MD - GENERAL HEALTH FORUM
Gee, George, it looks like you’re just one Big Ben Franklin whose mind knows no limits, venturing far afield, leaving no leaf unturned. I could say the same about Jackie! Your L paracasei appears to be dead. About 10 days ago I ordered some from India, which is not scheduled for delivery until mid April. Not holding my breath.by PC, MD - GENERAL HEALTH FORUM
There’s been a lot of controversy about whether ACE2 is good or bad with respect to COVID-19, since this seems to be the target receptor site for cellular entry. This controversy has expanded to involve ARBs, ACEIs, and NSAIDs in the therapeutic approach. Most of this controversy has spread across social media without any basis in fact. Although WHO initially agreed that ibuprofen should not bby PC, MD - GENERAL HEALTH FORUM
For the 33 v 40 NNT ref –%20Feb%202017by PC, MD - GENERAL HEALTH FORUM
I have search the internet somewhat comprehensively for the reference on the NNT for vitamin D supplementation versus the vaccine. I think it was a British study and Dr. Mercola references it on his website. And yes we all better buckle our collective seatbelts. Never let a good crisis go to waste. Mandatory vaccines will be the least of it.by PC, MD - GENERAL HEALTH FORUM
You are all most welcome. I've been in self enforced quarantine for the last 16 years since retirement (ha ha) and have nothing but time. Joy of reading is a gift for which I am most thankful. Joe, Good question! The same can be said for Vitamin D. It only takes 33 people supplementing with Vitamin D to prevent a single case of the flu, while 40 must be vaccinated to achieve the samby PC, MD - GENERAL HEALTH FORUM
? for sudden hearing lossby PC, MD - GENERAL HEALTH FORUM
Hi George, You must have gotten writers cramp with that long post. And I thought I was bad. The only reason you don’t have Alzheimer’s disease is due to your plentiful vitamin D intake, which inhibits renin. Hi Wolfpack, Your speculation is probably correct about off label use of Losartan. Alternatively it may just be in short supply, as most of these meds come from China. You might consby PC, MD - GENERAL HEALTH FORUM