First, a big thank you to Colin, for his keen eye in sleuthing out the discrepancies in nattokinase product labeling and all his extensive efforts to help clarify for us.
Of critical importance:
Those relying on the nattokinase enzyme to reduce or break down fibrin in blood and, therefore, reduce hyperviscosity or the tendency for blood to clot more easily - especially during bouts of arrhythmia - should be using the brand that has the science backing the efficacy and therefore, the safety factor.
In my original posts on the nattokinase topic from long ago..(around 2002 and going forward), all emphasized the importance of the NSK-SD® (label designation) because of the efficacy studies by Hiroyuki Sumi, PhD which are the standard upon which several nattokinase supplements were formulated and marketed. That still stands today. Although many bottlers marketing newer versions claim to be authentic, the label often belies that fact.
The question to ask about the brand of Nattokinase you choose, should always include:
• A significant amount of clinical and laboratory research is based upon NSK-SD brand of Nattokinase.
Does your brand contain NSK-SD exclusively? (emphasis:
exclusively)
• It’s also critical to understand that blends of enzymes may block or lyse nattokinase when encapsulated thus negating the therapeutic effect of NSK-SD.
Following are a few of many links to verify the science and efficacy behind the NSK-SD brand/labeling:
NSK-SD produced by Japan BioScience (JBSL) the company that did the testing on the NK enzyme efficacy and patented that strain.
[
www.ethorn.com]
[
www.jbsl-net.com]
Japan Nattokinase Association JNKA
[
www.ethorn.com]
The JNKA mark is only available for the one specific brand of nattokinase available through JBSL
Both Source Naturals and Nutricology brands have the designation right on the front label of the bottle… NSK-SD ®… and the back label also indicating the NSK-SD dose of 2000 FU’s /capsule or 100 mg/serving.
The Cardiokinase recommendation appeared on the forum in 2010 mentioned in a post
by Bill S
cardiokinase-new improved nattokinase
March 15, 2010 01:26AM [
www.afibbers.org]
After reading that and several other reports, I had posted several times referring to the comparison chart at the Cardiokinase website page that indicated this brand appeared to be the best but I am now going back to the science behind the NSK-SD nattokinase products… the one that helped me survive the clot in my heart so many years ago.
Thanks to Colin’s scrutiny and investigation, I am alerting everyone to understand the importance of sticking with the original recommendations on the NSK-SD® labeling.
For those who are concerned about the potential for soy sensitivities, there is the tried and true enzyme, lumbrokinase or Boulouke, that has many years of successful, safe usage as well.
References to Lumbrokinase and the original Nattokinase Conference Room series are listed below so new readers can research. Be sure to read through the posts on Viscosity Risk Factors at the end of the Lumbrokinase report.
Lumbrokinase [
www.afibbers.org]
Conference Room 39 Nattokinase [
www.afibbers.org]
Conference Room 40 Nattokinase [
www.afibbers.org]
Also - Great overall information in Hans Larsen's book:
Thrombosis and Stroke Prevention - Third Edition out this past May, 2018.
In closing, keep in mind that a prime influence on the hyperviscosity is silent inflammation so it's important to test for those markers so you can manage those out of range... see the post reference link on "Silent Inflammation - Risk of Stroke and MI" along with other posts on the topic.
Knowledge is power.
Jackie