Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Peptide Therapy in the Heart Disturbances, Myocardial Infarction, Heart Failure, Pulmonary Hypertension, Arrhythmias, and Thrombosis Presentation

All of the studies were done in rats, if they replicate to humans, this will be quiet awesome. BCP-157 seems to have an anti arrhythmic effect. I suggest to take a look at table n.3 in the study



[www.ncbi.nlm.nih.gov]

Promising, hopefully it will translate to humans . Thank you for the post/link!

"The BPC 157 therapy as antiarrhythmic agent follows the evidence that NO is commonly proposed as an endogenous cardioprotectant antifibrillatory factor [64,65] and that BPC 157 might modulate NO-effects (for review, see, i.e., [60]), and thereby might have a consistently strong beneficial effect against various arrhythmias and various agents and procedures that might produce arrhythmias"

The above got me wondering if there were any references with NO & afib. Found this paper. "Effects of NO Modulation on Cardiac Arrhythmias in the Rat Isolated Heart" Also this paper, "Strong humming for one hour daily to terminate chronic rhinosinusitis in four days: A case report and hypothesis for action by stimulation of endogenous nasal nitric oxide production", by George Eby, who was a member here years ago. In the paper, "Coincidentally, the subject’s cardiac arrhythmias (PACs) were greatly lessened." (humming increases production of NO in the sinuses, some people have figured out how to hum on the inhale to increase NO even more than humming on the exhale)

Quote
GeorgeN
"The BPC 157 therapy as antiarrhythmic agent follows the evidence that NO is commonly proposed as an endogenous cardioprotectant antifibrillatory factor [64,65] and that BPC 157 might modulate NO-effects (for review, see, i.e., [60]), and thereby might have a consistently strong beneficial effect against various arrhythmias and various agents and procedures that might produce arrhythmias"

The above got me wondering if there were any references with NO & afib. Found this paper. "Effects of NO Modulation on Cardiac Arrhythmias in the Rat Isolated Heart" Also this paper, "Strong humming for one hour daily to terminate chronic rhinosinusitis in four days: A case report and hypothesis for action by stimulation of endogenous nasal nitric oxide production", by George Eby, who was a member here years ago. In the paper, "Coincidentally, the subject’s cardiac arrhythmias (PACs) were greatly lessened." (humming increases production of NO in the sinuses, some people have figured out how to hum on the inhale to increase NO even more than humming on the exhale)

Yes, the major mechanism seems involving NO. Perhaps a good idea would be to take L-citrulline not arginine, 3 times per day possibly along with daily Tadalafil for NO

BPC-157 is widely used for tissue regeneration/injury recovery but also protection if used before the assault, even neuronal protection. I'm not sure what the heart and cardiovascular system goes through with AFIB, but it may be protective during Afib episodes.

Quote
Marco
Yes, the major mechanism seems involving NO. Perhaps a good idea would be to take L-citrulline not arginine, 3 times per day possibly along with daily Tadalafil for NO .

Worth a try.

Quote
Joe

Yes, the major mechanism seems involving NO. Perhaps a good idea would be to take L-citrulline not arginine, 3 times per day possibly along with daily Tadalafil for NO .

Worth a try.

Just looked up Tadlfil . I think the L-citrulline try is enough, wouldn't want to muddy the results

Has any forum member had experience of taking Tadalafil whilst in AF?
Did anything happen?
I would be very interested to know, and statistically there must be lots of individuals with both AF and ED.
I took my normal ED dose and reverted to sinus rhythm within two hours and AF didn’t recur for well over 24hours.
Repeating the Tadalafil at a reduced dose ( 17 hours half life ) got me back to sinus rhythm again in 2hours.

Quote
Phil2
Has any forum member had experience of taking Tadalafil whilst in AF?
Did anything happen?
I would be very interested to know, and statistically there must be lots of individuals with both AF and ED.
I took my normal ED dose and reverted to sinus rhythm within two hours and AF didn’t recur for well over 24hours.
Repeating the Tadalafil at a reduced dose ( 17 hours half life ) got me back to sinus rhythm again in 2hours.

wow, that is amazing, thanks for writing your experience here. What dose of Tadalafil are you using?



Edited 1 time(s). Last edit at 10/18/2023 11:57PM by Marco.

Quote
Phil2
Has any forum member had experience of taking Tadalafil whilst in AF?
Did anything happen?
I would be very interested to know, and statistically there must be lots of individuals with both AF and ED.
I took my normal ED dose and reverted to sinus rhythm within two hours and AF didn’t recur for well over 24hours.
Repeating the Tadalafil at a reduced dose ( 17 hours half life ) got me back to sinus rhythm again in 2hours.

Years ago there was a Swedish chemist who went by Gunnar who used cialis for his afib. Gunnar's posts: [www.afibbers.org]

I think he mentions our old conference room in some posts. Accessing it now is not obvious, so it is here: [www.afibbers.org]

I think 70 was his session: [www.afibbers.org]