Paxlovid while on Eliquis

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Combined P-gp and strong CYP3A4
inhibitors increase blood levels of
apixaban and increase the risk of
bleeding. Dosing recommendations
for co-administration of apixaban
with PAXLOVID depend on the
apixaban dose. Refer to the
apixaban product label for more
information.

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Ritonavir may significantly increase the blood levels of apixaban. This can increase the risk of serious or life-threatening bleeding complications. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Carey
I wouldn't be self-dosing with this one. I'd say people need to consult the EP who prescribed their anticoagulant and understands the individual medical issues. Clotting risk, bleeding risk, and kidney and liver function would all be considerations. Way above the pay grade of anyone here.