LDL and AF. Higher LDL helps?

Irish student finds link between high LDL and AF. Thesis is that AF caused by lowering APD of heart muscle cells and this is due to changes in heart muscle cells and macrophages. Macrophages are immune cells attached to the heart muscle cells by protein called Cx43. Increased levels of LDL affects the expression of Cx43 and this decreases the connection between the macrophages and heart tissue which in turn increases the APD.

If you enlarge the picture in the tweet below you can read the summary.

[twitter.com]



Edited 1 time(s). Last edit at 01/24/2020 07:55AM by Brian_og.