Resveratrol for stopping afib

I thought I would post the following email I recently received thinking that it may be beneficial for others to try.

I have had paroxysmal vagally mediated A-fib for a few years, and since taking Resveratrol (polygonum cuspidatum) root extract (I use Pure Encapsulations brand), it has disappeared completely, unless I get very very overtired, but then I can get rid of it (convert/ revert) much easier and faster than before. My previous triggers no longer set it off. Resveratrol works quickly, I just empty some of the powder into my mouth and hold it there - that is how it is best absorbed.

Hans

Hans, I don't really know what kind of Afib I have...I've been in Afib since last May a year ago..my heart beat stays around 80 most of the time..Before this last year, I had been on Amiodarone for about 2 or 3 years without an episode. Before that I had 8 or 9 cardioversions over a period of 7 years. I went into the hospital last May with a hemetoma and that brought on my Afib...My Cardiologist is just keeping my BP in check with meds.so far..
Do you think it would be a good idea for me to try Resveratrol? Would it be safe for anyone?
Thank you.....Nel

Hello Hans,

there has been a lot of comment about how a major or the major researcher on resveratrol falsified his results.

I realise this doesn't mean automatically that it has become useless or harmful but would appreciate your comments

thanks

Alex

What do you think about ranolazine for pip? See link below
[www.ncbi.nlm.nih.gov]

QT interval prolongation can be an issue with some meds. It appears that ranolazine can have this. Not that it is not a good choice, just something to be aware of.

From:
Contraindications

Ranolazine is known to increase the QT interval on the electrocardiogram.[12] While the mean increase in the corrected QT interval (QTc) is approximately 6 msec, about 5 percent of individuals may have QTc prolongations of 15 msec or longer.[13]

Extended QT intervals increase the risk of sudden cardiac death (SCD). The increase was 60% in adults, independently of other known risk factors, in an analysis of the Rotterdam Study.[14]

Because of this, caution should be taken when ranolazine is used in combination with other medications that increase the QT interval. In addition, because the effect of ranolazine on the QT interval is increased in the setting of liver dysfunction, it is contraindicated in persons with mild to severe liver disease.[1]

Normal dosing: 500 mg PO BID initially; may increase dose based on clinical symptoms, not to exceed 1000 mg PO BID
from:

Dose in the afib study: 2000 mg of oral ranolazine.

Hello,

Thanks Hans for posting about reservatrol- what would the dosing be? There is some interesting research on this and ventricular arrythmias in rats-
Did the writer of the post use this as a daily supplement and for an episode as well?
I'd like to try it but wonder about brands and dose

Tx
Lisa

That scandal only effected a small amount of research by one Indian PhD and the many benefits of resveratrol have been confirmed with numerous other uncontested research using tried and true methodolgies.

Its a myth too that this doc in question was THE major resveratrol researcher or even A major researcher in the field as had been initially reported to make the story more juicy sounding. A general opinion on the matter after all this had been investigated and sorted through from a large group of genuine active resveratrol and pterostilbene researches all agree that this guys cheating binge do not, in any way, lessen or impune all the other well done research results pointing to resveratrol's potential benefits and limitations.

Apparently the falsification he did was mainly to save time and expense in his own labs research and yet you can easily draw a well vetted conclusion about resveratrol from a mountain of other well designed studies that have nothing to do with this guy.

Typical hype story in the press that added more confusion than clarity to the real issue.
Shannon

Bad or dishonest research aside, resveratrol does have benefits for many, and for me, it stopped my paroxysmal vagally mediated A-fib. This is an empirical result, for just me, and everyone is different. Richard

Richard,

What is your brand, dose and timing for taking resveratrol if you don't mind my asking?

Tx,
Lisa

I was just in a-fib 10 hours. Just now converted after taking one tab of of KAL Ultra Max Resveratrol and 5 mg. sublingual pregnenolone. Not sure which did it or if it was coincidence.

Hans:

I posted a reply to this thread, but it does not seem to move up to the top of the forum list.

Lynn,

The latest post on the thread does not appear at the top. The postings are in date order as they are posted.

Hans

Quote
Richard Conrad
Bad or dishonest research aside, resveratrol does have benefits for many, and for me, it stopped my paroxysmal vagally mediated A-fib. This is an empirical result, for just me, and everyone is different. Richard

Richard, are you still Afib free? Which brand did you use?
Thank you