Journal of Nanobiotechnology 29 June 2005. Full text [
www.jnanobiotechnology.com]
Interaction of Silver Nanoparticles With HIV-1.
Jose Luis Elechiguerra, Justin L Burt, Jose R Morones, Alejandra Camacho-Bragado, Xiaoxia Gao, Humberto H Lara, and Miguel Jose Yacaman
Department of Chemical Engineering, The University of Texas at Austin, Texas.
Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, Mexico
Abstract
"The interaction of nanoparticles with biomolecules and microorganisms is an expanding field of research. Within this field, an area that has been largely unexplored is the interaction of metal nanoparticles with viruses. In this work, we demonstrate that
silver nanoparticles undergo a size-dependent interaction with HIV-1, with nanoparticles exclusively in the range of 1 -10 nm attached to the virus. The regular spatial arrangement of the attached nanoparticles, the center-to-center distance between nanoparticles, and the fact that the exposed sulfur-bearing residues of the glycoprotein knobs would be attractive sites for nanoparticle interaction suggest that silver nanoparticles interact with the HIV-1 virus via preferential binding to the gp120 glycoprotein knobs. Due to this interaction, silver nanoparticles inhibit the virus from binding to host cells, as demonstrated in vitro."
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US Patent 5,676,977 (Oct. 14, 1997) [
patft.uspto.gov]
Method of curing AIDS with tetrasilver tetroxide molecular crystal devices
Abstract
The diamagnetic semiconducting molecular crystal tetrasilver tetroxide (Ag.sub.4 O.sub.4) is utilized for destroying the AIDS virus, destroying AIDS synergistic pathogens and immunity suppressing moieties (ISM) in humans.
A single intravenous injection of the devices is all that is required for efficacy at levels of about 40 PPM of human blood. The device molecular crystal contains two mono and two trivalent silver ions capable of "firing" electrons capable of electrocuting the AIDS virus, pathogens and ISM. When administered into the bloodstream, the device electrons will be triggered by pathogens, a proliferating virus and ISM, and when fired will simultaneously trigger a redox chelation mechanism resulting in divalent silver moieties which chelate and bind active sites of the entities destroying them. The devices are completely non-toxic. However, they put stress on the liver causing hepatomegaly, but there is no loss of liver function.
Edited 1 time(s). Last edit at 05/24/2012 04:07PM by Erling.
