Quotesusan.d It was an abdominal ct. I’m patiently waiting to hear back on what tests will be done next. An endoscopy for sure for my gerd and in addition a colonoscopy or a sigmoidoscopy to peek to see why I had a GI bleed last year and check on the polyp they saw-something about a tag by the polyp. I will be bringing printed links you supplied. Thanks again Marco. HI Susan how are you doby Marco - AFIBBERS FORUM
Quotesusan.d Good find Marco! Thanks Aspirin is not usually GI friendly for a few and possibly poses a bleed factor if one is on a NOAC?? A family member has such a GI bleed from aspirin therapy that his affected bowels had to be removed. Apirin is not usually GI friendly because it generally come with many bad fillers, but there is still out there some pure apirinby Marco - AFIBBERS FORUM
QuotePhil2 Has any forum member had experience of taking Tadalafil whilst in AF? Did anything happen? I would be very interested to know, and statistically there must be lots of individuals with both AF and ED. I took my normal ED dose and reverted to sinus rhythm within two hours and AF didn’t recur for well over 24hours. Repeating the Tadalafil at a reduced dose ( 17 hours half life ) gotby Marco - AFIBBERS FORUM
QuoteCarey I wasn't saying you're wrong. It just seems like a rash decision to me since you've used the drug before without problems. I'm trying to avoid anything that could trigger it for now. I only use half of the RX dose, which 5 mg.by Marco - AFIBBERS FORUM
QuoteCarey Because of a single case history? You've used it a couple of times with no ill effect. In that case history the patient used it once and immediately developed new onset afib. Seems kind of different to me. Non-sedating antihistamine drugs and cardiac arrhythmias – biased risk estimates from spontaneous reporting systems? Abstract This study used spontaneous reportsby Marco - AFIBBERS FORUM
My doc prescribed this antihistamine called Cetirizine, I used it a couple of times but looking into the literature there may be some concerns for Afib, I think I will stop taking it. Atrial fibrillation (AF) is the most common observed arrhythmia in clinical practice. AF significantly increases the risk of thromboembolic ischemic stroke, and it results in affecting hemodynamic impairment.by Marco - AFIBBERS FORUM
on MIce, but it would be good if it would replicate to humans. Abstract Background/aims: Cardiac interstitial fibrosis is an abnormality of various cardiovascular diseases, including myocardial infarction, hypertrophy, and atrial fibrillation, and it can ultimately lead to heart failure. However, there is a lack of practical therapeutic approaches to treat fibrosis and reverse the damage to tby Marco - AFIBBERS FORUM
Quotesusan.d Thanks marco. I’ll print your studies to show the chief at the GI department where I go. I got the CatScan CD but am waiting for the results. The CT prep was horrible yesterday, I’m allergic to iodine contrast and this country’s protocol is 50mg prednisone 13 hours beforehand, 50mg 7 hours beforehand and then a third 50mg one hour before with a generic Benadryl. Having 150mg predby Marco - AFIBBERS FORUM
Quotesusan.d Thanks marco. I’ll print your studies to show the chief at the GI department where I go. I got the CatScan CD but am waiting for the results. I'm attaching two more studies, I may repeat some links I have already showed you, but there is 100% a connection between GERD and Afib, the potential mechanism is explained in the studies. It has something to do with literally pushinby Marco - AFIBBERS FORUM
HI Jackie, do you know if Propafenone has also the Fluoride?by Marco - GENERAL HEALTH FORUM
Quotesusan.d Part of my problem was laziness with using my cpap on vacations. I was on flecainide successfully for 15 years and went overseas for 5 weeks and I didn’t pack my cpap equipment due to lack of carry on and check in space and weight restrictions. My afib came back. So since then I have used it religiously except for this week because it was 105 degrees and I was carrying too much on thby Marco - AFIBBERS FORUM
Quotesusan.d Thanks Marco! Check out the GERD/CPAP link I just shared in the general forum. that's interesting. I have been using a CPAP machine for a mild sleep apnea, and I was thinking if there was any connection to it. Thanks for sharing the linkby Marco - AFIBBERS FORUM
Quotesusan.d Marco- looking forward to reading the study Hi Susan, I made a new post with the study, but I will attach the link to it at the bottom of this comment for you. This is a quote from Hippocrates: "All disease begins in the gut" This is a study that was recently publishedby Marco - AFIBBERS FORUM
QuoteSimonR Thanks very interesting, my vagaly triggered PACs and afib always seems to be gut related. I'm also pretty sure my 3 times I went into Afib the trigger was always gut/stomach related. I believe endotoxins and gut dysfunction may play a major role in Afib. This is a new study that was just published this year, it should be a major sticky post on the forum, I believe.by Marco - AFIBBERS FORUM
New Study worth the reading. I suggest to open the link to see the images as well. Therapeutic Implications Despite the current lack of human studies to support interventions aimed at modifying the gut microbiota in the prevention and management of AF, recent preclinical animal studies have highlighted the potential impact of gut microbiota modification on AF susceptibility.62,63 Zhangby Marco - AFIBBERS FORUM
QuoteGeorgeN Conclusions In conclusion, we observed a different microbiome composition in prevalent and incident AF compared to non-affected individuals with a number of genera and species which differed in abundance. /quote] Some years ago (5?), my wife & I were consulting with our "longevity" doc. Independently, we'd gotten a stool sample test of our fecal microbiome.by Marco - AFIBBERS FORUM
Gut microbiome and atrial fibrillation—results from a large population-based study Conclusions In conclusion, we observed a different microbiome composition in prevalent and incident AF compared to non-affected individuals with a number of genera and species which differed in abundance. Overall, the alpha and beta diversity of the gut microbiome did not meaningfully discriminate individualsby Marco - AFIBBERS FORUM
Quotesusan.d I’m getting tested in less than two weeks to see if I have it. The horse already left the gate (since I’m av nuked) but it will give me closure on why I couldn’t get “fixed”. They are starting with a CT with contrast and then a endoscopy. I will say Multaq aggravated my GERD because one of its listed side effects is acid reflux. I am no longer on multaq or any arrhythmia drug butby Marco - AFIBBERS FORUM
I may conclude my research about SFA effecting Afib with this study. My conclusion is that excess Palmitic acid is associated with increased incidence of Afib, we have a rat interventional study using Palm Oil which is high in Palmitic Acid, and two human studies pointing out the issue with Palmitic acid and Afib as well. However, excess Palmitic acid in the blood is obtained by constantlyby Marco - AFIBBERS FORUM
I'm finishing to read Dr Dean Book on Magnesium, she recommends nearly for everyone 600/900mg of elemental magnesium to recover a deficiency or 6-10mg Kg body weight to bring Mg RBC at 6.0 to 6.5, , or for athletes or people who exercise regularly 10-15 mg kg. I believe more in line with what George has been doing to keep a good healthy level of Mg RBC.by Marco - AFIBBERS FORUM
Quotesusan.d My gosh Marco, thanks! I’ve been complaining for decades about my Afib and GERD being so bad I still get acid vomiting plus beish ng anemic (getting iron iv), pain in my chest and bowel obstruction. Nobody connected the possibility of a hiatal hernia. All my complaints went to deaf ears. Multag made it worst and I would just get Afib after vomiting acid. My GP, GI and cardiologist suby Marco - AFIBBERS FORUM
I just want to make a note for someone who may read this. GERD and gastrointestinal mobility issues may point out to a suboptimal thyroid and adrenal function.by Marco - AFIBBERS FORUM
QuoteGeorgeN I was using the Dr Best Glycinate/Lysinate years ago, till I was told that they started to buy their raw material from China and I stopped. Do you know anything about this? I have no info one way or the other. Apparently the story about Dr Best, is that it was bought by a Chinese company in the 2016.by Marco - AFIBBERS FORUM
this is a Radio Podcast about the Roemheld Syndrome: The Gastric - Cardiac Connection. I don't believe they mention Afib, but PVC's and tachycardia for sure.by Marco - AFIBBERS FORUM
I have to say that in all my 3 episodes of Afib, there was 100% a gastric connection, that sensation of my stomach being full-blooded. Today I went to talk about this with my Primary, and of course he negated the possibility out of his ignorance, and to talk about this with the EP. For those who have or think have the gastrointestinal connection to Afib, this is a good study to read in fullby Marco - AFIBBERS FORUM
QuoteGeorgeN The Doctor's Best website says they are cGMP "What is CGMP? CGMP refers to the Current Good Manufacturing Practice regulations enforced by the FDA. CGMP provides for systems that assure proper design, monitoring, and control of manufacturing processes and facilities. Adherence to the CGMP regulations assures the identity, strength, quality, and purity of drug products bby Marco - AFIBBERS FORUM
as right now, I couldn't find any meaningful evidence supporting this in humans, beside this study below. But unless someone is type 2 diabetic or possibly gargling Palm oil, there should not be an issue with intracellular Ca activation and other SFA's Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes Abstract Free fatty acids (FFAs) are important sby Marco - AFIBBERS FORUM
Quotegloaming Plant oils with high concentrations of linoleic acid are death. I don't blame the mice for their verdict. Palm oil has about 10% linolenic acid, perhaps enough to cause the trouble at 45/60% of tot caloriesby Marco - AFIBBERS FORUM
QuoteGeorgeN In general mice don't do well on high fat diets. Here is a Nature article on the topic. thanks for the article. However, in the first study I linked, mice were still fed a high fat diet but when Olive Oil was used, there was no reported NOX2 activation. Below a quote from the study. Of course, in mice not humans. "These findings indicate that a HSFD can cause the sameby Marco - AFIBBERS FORUM
To note. If I remember well, when are overweight but especially obese, our liver will start producing palmitic acid from excess carbohydrates. That is why in the studies they mentioned more than once obesity and diabetes, as our body will overproduce Palmitic acid in these two conditions. A possible connection.by Marco - AFIBBERS FORUM