New Vitamin D study shows key link to inflammation reduction

http://www.medscape.com/viewarticle/821184?nlid=50465_2121&src=wnl_edit_medn_card&uac=6588DG&spon=2]Vitamin D reduces systemic inflammation[/url]

This latest study in Vitamin D gives a big boost to the anti-inflammatory action of Vitamin D3 being one of its major pathways of positive action in the body. It also is fully in line with and builds on a number of early studies and suppositions about Vitamin D3 mechanisms that, combined, strongly reinforce this relationship between Vitamin D3 serum levels ... known as the 25(OH)D3 test ... and underscores its potential role in helping to reduce CVD as well as nearly all chronic diseases in which inflammation plays such a core role. In other words, nearly all chronic diseases associated with aging.

Vitamin D3 is quite inexpensive and I encourage all of our readers who don't have one of the rare contraindications to it such as Sarcoidosis or non-Hodgkins Lymphoma to start taking 5,000iu a day of high quality oil-based Vitmain D in either soft gel capsules or liquid drops (avoid the white powder forms in general as they tend to have poorer absorption).

Its important that after about three months you get Vit D3 - 25(OH)D3 test either though your GP or without a doctor visit but buying the simple to use and highly accurate ZRT Lab Vitamin D3 finger prick test you can do without a prescription from your own home and send back for results in about 10 days.

Here is the link to ZRT Labs: Vitamin D Blood spot home test. It cost a very reasonable $75.00 for those without a ready doc to order the test and good insurance to pay for a venous blood draw test and the ZRT test had been dhown independently to be just as accurate as venous testing.

Ideal range for this test is between 60 and 80ng/ml so if you are below that number after 3months at 5,000iu then increase your dose by either 1,000 to 2,000 IU (depending how far away you are from the sweet spot range) and retest in another 3months . If you are too high and particular if you get close to 100 or above then reduce you dose accordingly and retest in 3 months until you find the right dose to maintain this optimal healthy range.

Make sure you take your D3 each day with the largest fat containing meal of the day or at least with something like a tablespoon of extra voting coconut oil, almond butter or yogurt etc . You will find a huge increase in absorption of all fat soluble vitamins when taken directly with a healthy dose of good quality dietary fats.

The same is true for Vitamin K1 & K2, Vitamin E and Vitamin A (retinol form). It is also very wise to insure proportional supplementation with these other three fat soluble nutrients all together as they mutually balance each other and too much of one without a good dose of the others can lead to gradual depletion of the ones not supplements for, particular if your diet lacks a reliable source for these vital nutrients.

This potential benefit of insuring optimal Vitamin D3 blood levels for us afibbers is underscored by the video McHale kindly posted of NBC medical reporter Dr Sanjay Gupta interviewing EP Dr Vivek Reddy recently in this thread. Please watch this video if you have not about the key role of inflammation in not only AFIB but in most other such chronic diseases. http://www.afibbers.org/forum/read.php?9,143968]Vivek Reddy interview with Sanjay Gupta in McHale's thread[/url].

This is an important topic and Adequate vitamin D can definite help reduce inflammatory markers in the body and should be a key part of nearly everyone's anti-inflammatory efforts.

Don't just wing it, though, do the simple testing and dose adjustment protocol as noted above, you only need to confirm you are in the right range and not too high or too low and then just continue with that maintenance dose indefinitely. Be sure and add Vitamin K2-MK7 too and Vitamin A and a mixed tocopherol or tocotrienol form of Vitamin E as well.

Shannon



Edited 2 time(s). Last edit at 03/03/2014 12:24PM by Shannon.

We were just talking about this yesterday. Comparing the health of the elders in our family. Those that lived and live in the northeast have had really bad arthritis compare to Socal cohorts. I think because of the amount of sun exposure especially this time of the year. And there were other problems besides arthritis. Vit D is really critical in many different nutritional absorption and inflammation pathways

Very helpful post. Thanks!

Sound great to me too....Nel

This is a quote from Consumer Labs Vitamin D review showing a significant association of increased survival of women with breast cancer with higher levels of Vitamin D3... the 32.4ng/ml they show is still a too low level but better than the lower values below 30ng/ml a more optimal range is around 60ng/mg to 75ng/ml or so, staying well below 100ng/ml.


...In addition, an analysis of five clinical studies found that women who had the highest vitamin D blood levels at the time of breast cancer diagnosis were twice as likely to survive during the studies (which lasted 5 to 20 years) as women with the lowest vitamin D levels (Mohr, Anticancer Research 2014). Due to differences in the studies analyzed, the "low" vitamin D groups included women with less than 14 to 30 ng/mL of vitamin D while the "high" groups included those with more than 22 to 32.4 ng/mL. While this association between vitamin D levels and mortality with breast cancer is not proven to be "cause-and-effect," the researchers noted that there is no scientific reason to believe that breast cancer would cause a decrease in vitamin D. Consequently, they suggest patients with breast cancer maintain vitamin D levels of "30 to 80 ng/mL."