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"The mechanism behind how beta-carotene supplementation increases CVD risk is not yet fully known," notes Burdeos. "[However,] adequate evidence shows the supplement form of beta carotene has no cardiovascular benefit."
Don't know if anybody takes this supplement but I wouldn't take it. Many years ago I started taking beta-carotene and got an aura migraine everyday after taking it, I finally realized that beta-carotene was responsible for my auras, I quit and no more aura migraines.