The Carb Addiction Doc on Colchicine vs. statins I follow Dr. Rob Cywes, the Carb Addiction Doc for another viewpoint on heart and glucose health. This latest video is a bit of an eye opener for me because my wife was put on colchicine for about 8 weeks before she consulted a rheumatologist who promptly took her off it. I haven't seen my wife more energetic or feeling well, and very much her ol' self, than about four weeks into the 8 week span on colchicine. Also, it was the link to pulmonary vein energizing and AF that caught my ear. Take this for what it's worth to you: [www.youtube.com] https://www.afibbers.org/forum/read.php?9,196602,196602#msg-196602 Tue, 25 Aug 2026 02:56:19 +0000 Phorum 5.2.23 https://www.afibbers.org/forum/read.php?9,196602,196746#msg-196746 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196746#msg-196746 californiagal AFIBBERS FORUM Sun, 28 Jul 2024 00:19:28 +0000 https://www.afibbers.org/forum/read.php?9,196602,196687#msg-196687 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196687#msg-196687
... disgusting.

At any rate, an OUTSTANDING video... thank you.]]> Boatner AFIBBERS FORUM Tue, 23 Jul 2024 22:35:59 +0000 https://www.afibbers.org/forum/read.php?9,196602,196635#msg-196635 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196635#msg-196635 Carey AFIBBERS FORUM Fri, 19 Jul 2024 05:24:42 +0000 https://www.afibbers.org/forum/read.php?9,196602,196634#msg-196634 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196634#msg-196634 gloaming AFIBBERS FORUM Fri, 19 Jul 2024 04:41:16 +0000 https://www.afibbers.org/forum/read.php?9,196602,196633#msg-196633 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196633#msg-196633
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gloaming
So, I would like to understand what the authors mean by 'coronary artery disease'. Is it the slightest indication of plaque...somewhere...anywhere...or are we talking about 40% occlusion and up?

This seems to be the one referenced study that looked at the question you are asking.

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Trial Population
Patients 35 to 82 years of age were eligible if they had any evidence of coronary disease on invasive coronary angiography or computed tomography angiography or a coronary-artery calcium score of at least 400 Agatston units on a coronary-artery calcium scan. Patients were required to have been in a clinically stable condition for at least 6 months before enrollment. Patients were not eligible if they had moderate-to-severe renal impairment, severe heart failure, severe valvular heart disease, or known side effects from colchicine. Renal function was defined on the basis of the Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for Acute Kidney Injury.
]]> GeorgeN AFIBBERS FORUM Thu, 18 Jul 2024 20:51:24 +0000 https://www.afibbers.org/forum/read.php?9,196602,196632#msg-196632 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196632#msg-196632
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gloaming
So, I would like to understand what the authors mean by 'coronary artery disease'. Is it the slightest indication of plaque...somewhere...anywhere...or are we talking about 40% occlusion and up?

The only indication of CAD I've ever gotten was a description of "mild aortic plaque" from one TEE (I've had others, but only one TEE ever mentioned it). That was sufficient to get me in the Watchman FLX clinical trials because they required a CHADS-Vasc of 3+. My EP at the time (Natale) and I had always considered myself a 2 for 65+ and HTN, but he successfully used that one report to get me included after the research team rejected me as a CHADS-Vasc 2.

So the answer is any plaque at all means you have CAD. The thing is, virtually every single person over 65 has at least some detectable plaque, so take it for what it's worth. If you really want an assessment, get a calcium score.]]> Carey AFIBBERS FORUM Thu, 18 Jul 2024 20:38:44 +0000 https://www.afibbers.org/forum/read.php?9,196602,196627#msg-196627 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196627#msg-196627
So, I would like to understand what the authors mean by 'coronary artery disease'. Is it the slightest indication of plaque...somewhere...anywhere...or are we talking about 40% occlusion and up?]]> gloaming AFIBBERS FORUM Thu, 18 Jul 2024 18:47:03 +0000 https://www.afibbers.org/forum/read.php?9,196602,196622#msg-196622 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196622#msg-196622
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colindo
Is there any anyone who has had success with colchicine stoping their Afib.
I have never heard of anyone.

Looks like it may be beneficial in post surgical cases.

Source

The Effect of Colchicine on Atrial Fibrillation: A Systematic Review and Meta-Analysis

Abstract
Colchicine is a potent anti-inflammatory agent whose benefits have been explored for various conditions, including atrial fibrillation (AF). In this article, we tried to understand why colchicine might be beneficial in AF and reviewed various studies that looked at the effect of colchicine against AF. We followed the PRISMA algorithm and undertook a literature search to identify studies with control groups that looked at the effect of colchicine against AF and conducted a meta-analysis. We identified six studies on post-cardiac surgical patients, three on post-pulmonary vein isolation (PVI)/ablation patients, and two on coronary artery disease. In patients who underwent cardiac surgery, we found that colchicine is beneficial against postoperative atrial fibrillation (POAF) with a relative risk (RR) of 0.70 (95% CI of 0.58 to 0.84) and a p-value of 0.0001. We also found that in patients who underwent PVI/ablation, colchicine is beneficial in decreasing AF recurrence over three months with an RR of 0.57 (95% CI of 0.39 to 0.83) and a p-value of 0.0032 and over 12 months follow-up with an RR of 0.58 (95% CI of 0.42 - 0.80) and a p-value of 0.0008. Our meta-analysis showed that in patients with coronary artery disease, colchicine had no significant benefit in decreasing the incidence of AF with a hazard ratio (HR) of 0.86 (95% CI of 0.69 - 1.06) and a p-value of 0.16. From this study, we conclude that colchicine may be beneficial for decreasing the incidence of AF in post-cardiac surgery patients and post-PVI/ablation patients. It may not decrease the incidence of AF in patients with coronary artery disease.]]> GeorgeN AFIBBERS FORUM Thu, 18 Jul 2024 11:41:55 +0000 https://www.afibbers.org/forum/read.php?9,196602,196621#msg-196621 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196621#msg-196621 I have never heard of anyone.]]> colindo AFIBBERS FORUM Thu, 18 Jul 2024 10:50:50 +0000 https://www.afibbers.org/forum/read.php?9,196602,196614#msg-196614 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196614#msg-196614 gloaming AFIBBERS FORUM Wed, 17 Jul 2024 22:15:26 +0000 https://www.afibbers.org/forum/read.php?9,196602,196605#msg-196605 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196605#msg-196605
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gloaming
Also, it was the link to pulmonary vein energizing and AF that caught my ear.

Very interesting! Thanks Gloaming!]]> GeorgeN AFIBBERS FORUM Wed, 17 Jul 2024 11:37:08 +0000 https://www.afibbers.org/forum/read.php?9,196602,196603#msg-196603 Re: The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196603#msg-196603 MeganMN AFIBBERS FORUM Wed, 17 Jul 2024 04:44:03 +0000 https://www.afibbers.org/forum/read.php?9,196602,196602#msg-196602 The Carb Addiction Doc on Colchicine vs. statins https://www.afibbers.org/forum/read.php?9,196602,196602#msg-196602
[www.youtube.com]]]> gloaming AFIBBERS FORUM Tue, 16 Jul 2024 19:58:34 +0000