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        <title>Choosing NOAC Half Dosing</title>
        <description> Several long time ex-Afibbers here have chosen to continue half doses of various blood thinners, 2.5 mg Eliauis twice daily being the most mentioned.

Obviously a prescription is needed to source the pills so some physicians support this practice.

I have asked the NP who works with Dr. Natale where I had my ablation 16 months ago for Dr. Natale&amp;#039;s current opinion but have received no response.

For a brief history, My first Natale ablation was in 2007 after what was then called lone afib and flutter.  The afib came back in 2018 and I had a second Natale ablation in 2020 when he also ablated my LAA.  My 6 month TEE was tight enough that I didn&amp;#039;t need a Watchman, further NOAC&amp;#039;s or an aspirin and I am still in NSR today.  However, I am 85 years old and in otherwise good health with retular exercise of tai chi and farming.  I do, however, take a baby aspirin upon recommendation of my Cardiologist who says there are a lot more people in his hospital with strokes caused by blood clots than by excessive bleeding.  He thinks the one size fits all NOAC&amp;#039;s are binary, either they work as prescribed or they don&amp;#039;t work at all.  I had no significant bleeding issues when on full dose Eliquis, a walk in the park compared to the Warfarin I had to take in the early 2000&amp;#039;s.

Certainly my CHADS score alone would have me still on the medication.  I&amp;#039;m trying to decide what would be best for me.

Does anyone know of actual published studies about the risk/benefits of half dosing NOAC&amp;#039;s for ex-afibbers?  I can&amp;#039;t seems to find any.</description>
        <link>https://www.afibbers.org/forum/read.php?9,185621,185621#msg-185621</link>
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            <guid>https://www.afibbers.org/forum/read.php?9,185621,185669#msg-185669</guid>
            <title>Re: Choosing NOAC Half Dosing</title>
            <link>https://www.afibbers.org/forum/read.php?9,185621,185669#msg-185669</link>
            <description><![CDATA[ Here&#039;s one study from 2015, AVERROES. that seems to confirm your action, however the dosages seem to be pretty all wide for both Eliquis and Aspirin:<br />
<br />
[<a href="https://pubmed.ncbi.nlm.nih.gov/26590293/"  rel="nofollow">pubmed.ncbi.nlm.nih.gov</a>]<br />
<br />
They comment on VKA, (warfarin), treatment as being unsuitable for patients in their trial. <br />
<br />
They give the 2.5 mg Eliquis twice daily to selected patients and everyone else the 5 mg twice daily compared to different aspirin dosages.<br />
<br />
I&#039;m sure both Natale and my Cardiologist are aware of this and other related studies mentioned but I&#039;ll send the reference off to Natale&#039;s NP and my doc for hopeful thoughtful replies.]]></description>
            <dc:creator>ggheld</dc:creator>
            <category>AFIBBERS FORUM</category>
            <pubDate>Mon, 30 May 2022 13:29:55 +0000</pubDate>
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        <item>
            <guid>https://www.afibbers.org/forum/read.php?9,185621,185648#msg-185648</guid>
            <title>Re: Choosing NOAC Half Dosing</title>
            <link>https://www.afibbers.org/forum/read.php?9,185621,185648#msg-185648</link>
            <description><![CDATA[ I don&#039;t know of any studies looking at exactly that, but there are studies showing that Eliquis is superior to aspirin and has a lower bleed risk. That&#039;s why I chose to remain on half-dose Eliquis rather than taking a low-dose aspirin as Natale, my PCP, and my local EP all think I should. I&#039;m pretty confident Natale would say the same to you, so I would try to contact his NP again. If you can&#039;t reach them, you could also take the question to your cardiologist. If he&#039;s at all up to date on his continuing education on the subject he knows Eliquis is a safer, more effective choice (albeit much more expensive).]]></description>
            <dc:creator>Carey</dc:creator>
            <category>AFIBBERS FORUM</category>
            <pubDate>Sun, 29 May 2022 16:27:27 +0000</pubDate>
        </item>
        <item>
            <guid>https://www.afibbers.org/forum/read.php?9,185621,185621#msg-185621</guid>
            <title>Choosing NOAC Half Dosing</title>
            <link>https://www.afibbers.org/forum/read.php?9,185621,185621#msg-185621</link>
            <description><![CDATA[ Several long time ex-Afibbers here have chosen to continue half doses of various blood thinners, 2.5 mg Eliauis twice daily being the most mentioned.<br />
<br />
Obviously a prescription is needed to source the pills so some physicians support this practice.<br />
<br />
I have asked the NP who works with Dr. Natale where I had my ablation 16 months ago for Dr. Natale&#039;s current opinion but have received no response.<br />
<br />
For a brief history, My first Natale ablation was in 2007 after what was then called lone afib and flutter.  The afib came back in 2018 and I had a second Natale ablation in 2020 when he also ablated my LAA.  My 6 month TEE was tight enough that I didn&#039;t need a Watchman, further NOAC&#039;s or an aspirin and I am still in NSR today.  However, I am 85 years old and in otherwise good health with retular exercise of tai chi and farming.  I do, however, take a baby aspirin upon recommendation of my Cardiologist who says there are a lot more people in his hospital with strokes caused by blood clots than by excessive bleeding.  He thinks the one size fits all NOAC&#039;s are binary, either they work as prescribed or they don&#039;t work at all.  I had no significant bleeding issues when on full dose Eliquis, a walk in the park compared to the Warfarin I had to take in the early 2000&#039;s.<br />
<br />
Certainly my CHADS score alone would have me still on the medication.  I&#039;m trying to decide what would be best for me.<br />
<br />
Does anyone know of actual published studies about the risk/benefits of half dosing NOAC&#039;s for ex-afibbers?  I can&#039;t seems to find any.]]></description>
            <dc:creator>ggheld</dc:creator>
            <category>AFIBBERS FORUM</category>
            <pubDate>Sat, 28 May 2022 14:06:00 +0000</pubDate>
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