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        <title>Nattokinase Warning: Dislodge Blood Clots??</title>
        <description> Friends,

This morning I was looking to see what the latest scoop on nattokinase might be. On the Sloan Kettering website, under &amp;quot;Nattokinase -- Patient Warnings&amp;quot;, I read: &amp;quot;Theoretically, nattokinase can cause an existing clot to dislodge, resulting in a stroke or embolus at a distant location. Patients with a history of deep vein thrombosis should avoid of use nattokinase.&amp;quot;

Yikes!  Does anyone have any further information on this?  Is it a real concern?

Thanks, Lance</description>
        <link>https://www.afibbers.org/forum/read.php?10,189264,189264#msg-189264</link>
        <lastBuildDate>Wed, 24 Jun 2026 23:17:55 +0000</lastBuildDate>
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        <item>
            <guid>https://www.afibbers.org/forum/read.php?10,189264,189332#msg-189332</guid>
            <title>Re: Nattokinase Warning: Dislodge Blood Clots??</title>
            <link>https://www.afibbers.org/forum/read.php?10,189264,189332#msg-189332</link>
            <description><![CDATA[ Hi Lance -  Thanks for your good news that you remain &#039;safe&#039; with the use of nattokinase.      <br />
<br />
The August 2018 issue of Life Extension magazine published a report about clot formation and two extracts… nattokinase and French maritime pine bark  (pycnogenol)   – “ shown to prevent deadly clot formation&quot;  and. also,  to make clots that do develop more likely to resolve quickly.   (Supported by 34 related study references.and definitely worth noting.)<br />
<br />
While the report targets the risks of sitting too long and risk of Deep Vein Thrombosis, it also describes “ <i>Solutions to Deadly Clots, Deep Vein Thrombosis”…</i> and the use of anti-clotting Nattokinase and French Maritime Pine Bark Extract (pycnogenol)… as prevention measures and solutions. <br />
<br />
[<a href="https://www.lifeextension.com/magazine/2018/8/dangers-of-sitting-too-long"  rel="nofollow">www.lifeextension.com</a>]<br />
<br />
Best to you,<br />
Jackie]]></description>
            <dc:creator>Jackie</dc:creator>
            <category>GENERAL HEALTH FORUM</category>
            <pubDate>Thu, 02 Feb 2023 18:49:10 +0000</pubDate>
        </item>
        <item>
            <guid>https://www.afibbers.org/forum/read.php?10,189264,189329#msg-189329</guid>
            <title>Re: Nattokinase Warning: Dislodge Blood Clots??</title>
            <link>https://www.afibbers.org/forum/read.php?10,189264,189329#msg-189329</link>
            <description><![CDATA[ Thanks for this post, Jackie, and the reminder of all the sterling work you&#039;ve done on this forum over the years on this topic. I continue to use nattokinase daily, as initially inspired by your posts years back.<br />
<br />
I&#039;m especially happy to learn of the podcast you linked to. That was new for me, and helpful.<br />
<br />
My feeling is that the authors of the article I quoted above threw in the &quot;theoretical&quot; possibility of dislodged clots just to bolster their creds in terms of &quot;scientific objectivity&quot;.  I see this often among academicians.<br />
<br />
Warm regards,<br />
<br />
Lance]]></description>
            <dc:creator>ln108</dc:creator>
            <category>GENERAL HEALTH FORUM</category>
            <pubDate>Thu, 02 Feb 2023 17:56:56 +0000</pubDate>
        </item>
        <item>
            <guid>https://www.afibbers.org/forum/read.php?10,189264,189326#msg-189326</guid>
            <title>Re: Nattokinase Warning: Dislodge Blood Clots??</title>
            <link>https://www.afibbers.org/forum/read.php?10,189264,189326#msg-189326</link>
            <description><![CDATA[ [<a href="https://healthquestpodcast.com/199-nattokinase-and-cardiovascular-health-my-interview-with-dr-ralph-holsworth/Hi"  rel="nofollow">healthquestpodcast.com</a>] Lance -   You may recall that I had a clot form in my heart 3 mos. after my first ablation... after being cardioverted for breakthrough AF.... and by then, I was off Coumadin but had resumed the Nattokinase.  Back then (2003)... I also had learned about nattokinase for clot prevention from Ralph Holsworth, DO.  <br />
<br />
Here is a review post I offered in 2017 titled <b>&quot;Clot Risk&quot;</b> <br />
[<a href="https://www.afibbers.org/forum/read.php?9,157183,157183#msg-157183"  rel="nofollow">www.afibbers.org</a>]<br />
<br />
Jackie<br />
<br />
[<a href="https://healthquestpodcast.com/199-nattokinase-and-cardiovascular-health-my-interview-with-dr-ralph-holsworth/"  rel="nofollow">healthquestpodcast.com</a>]]]></description>
            <dc:creator>Jackie</dc:creator>
            <category>GENERAL HEALTH FORUM</category>
            <pubDate>Thu, 02 Feb 2023 16:13:03 +0000</pubDate>
        </item>
        <item>
            <guid>https://www.afibbers.org/forum/read.php?10,189264,189282#msg-189282</guid>
            <title>Re: Nattokinase Warning: Dislodge Blood Clots??</title>
            <link>https://www.afibbers.org/forum/read.php?10,189264,189282#msg-189282</link>
            <description><![CDATA[ OK, so I did some further research and I think I&#039;ve answered my own question. I looked up nattokinase on consumerlab.com, and they have essentially the same caution, with an almost identically worded &quot;theoretical&quot; warning in their &quot;Concerns and Cautions&quot; section of their review of the supplement. But they give a reference to a source article: Milner, Martin and Kouhei Makise, &quot;Natto and Its Active Ingredient Nattokinase: A Potent and Safe Thrombolytic Agent,&quot; <i>Alternative &amp; Complementary Therapies</i> 8 (June 2002): 157-154.<br />
<br />
I got hold of the article, and the full relevant quote is: &quot;Because natto is a very potent fibrinolytic agent, it is theorectically possible that regular use could break a clot loose from a lower-extremity vein and cause a pulmonary embolism or pass upward and cause a stroke.&quot; <br />
<br />
However, they go on to seemingly minimize their caution: &quot;Since the flurry of research began on natto in the 1980s, use of natto as a health-enhancing whole food has dramatically increased in Japan.In spite of this increase, there have been no reported side-effects, complications or clot mobilizations. Although no controlled studies have been conducted to demonstrate natto&#039;s safety with regard to avoiding clot mobilization, historically, documentation records that natto is significantly safe&quot; (163).  The conclusion of the article speaks of &quot;nattokinase&#039;s effectiveness and safety for managing a wide range of diseases&quot; (163).<br />
<br />
This, along with the &quot;Safe&quot; in the title of the article, leads me to conclude that the author&#039;s estimate if the risk of nattokinase dislodging a clot is very &quot;theoretical&quot; indeed.<br />
<br />
Though now 20-years old, the article is an interesting read.  <a href="https://www.dropbox.com/s/rcnl3gcbea5taio/Milner%20and%20Makise%202004%20Natto%20and%20Nattokinase%20-%20Potent%20and%20Safe%20Thrombolytic%20Agent.pdf?dl=0"  rel="nofollow">There&#039;s a copy here</a>. I&#039;ll leave it up for a few weeks.]]></description>
            <dc:creator>ln108</dc:creator>
            <category>GENERAL HEALTH FORUM</category>
            <pubDate>Sat, 28 Jan 2023 16:36:49 +0000</pubDate>
        </item>
        <item>
            <guid>https://www.afibbers.org/forum/read.php?10,189264,189264#msg-189264</guid>
            <title>Nattokinase Warning: Dislodge Blood Clots??</title>
            <link>https://www.afibbers.org/forum/read.php?10,189264,189264#msg-189264</link>
            <description><![CDATA[ Friends,<br />
<br />
This morning I was looking to see what the latest scoop on nattokinase might be. On t<a href="https://www.mskcc.org/cancer-care/integrative-medicine/herbs/nattokinase"  rel="nofollow">he Sloan Kettering website</a>, under &quot;Nattokinase -- Patient Warnings&quot;, I read: &quot;Theoretically, nattokinase can cause an existing clot to dislodge, resulting in a stroke or embolus at a distant location. Patients with a history of deep vein thrombosis should avoid of use nattokinase.&quot;<br />
<br />
Yikes!  Does anyone have any further information on this?  Is it a real concern?<br />
<br />
Thanks, Lance]]></description>
            <dc:creator>ln108</dc:creator>
            <category>GENERAL HEALTH FORUM</category>
            <pubDate>Fri, 27 Jan 2023 16:00:45 +0000</pubDate>
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