My doctor just suggested to me to take quercetin for my allergies and sinusitis. While I researched it online I came across a study suggesting quercetin can help with afib. Any thoughts? And is quercetin safe to take? https://www.afibbers.org/forum/read.php?10,187809,187809#msg-187809 Thu, 25 Jun 2026 10:12:57 +0000 Phorum 5.2.23 https://www.afibbers.org/forum/read.php?10,187809,188550#msg-188550 https://www.afibbers.org/forum/read.php?10,187809,188550#msg-188550
Quercetin improves atrial fibrillation through inhibiting TGF-β/Smads pathway via promoting MiR-135b expression

Results: The expression of miR-135b was downregulated, and those of TGFBR1, TGFBR2, target genes of miR-135b were upregulated in human AF tissues and negatively regulated by miR-135b in RCFs. Through inhibiting TGF-β/Smads pathway via promoting miR-135b expression, quercetin treatment inhibited proliferation, myofibroblast differentiation and collagen deposition in ISO-treated RCFs, as evidenced by reduced expressions of cyclin D1, α-SMA, collagen-related genes and proteins, and alleviated fibrosis and collagen deposition of atrial tissues in ISO-treated rats.

Conclusion: Quercetin may alleviate AF by inhibiting fibrosis of atrial tissues through inhibiting TGF-β/Smads pathway via promoting miR-135b expression.

[pubmed.ncbi.nlm.nih.gov]

Numerous more studies here [pubmed.ncbi.nlm.nih.gov]]]> PavanPharter GENERAL HEALTH FORUM Fri, 09 Dec 2022 22:11:22 +0000 https://www.afibbers.org/forum/read.php?10,187809,187809#msg-187809 https://www.afibbers.org/forum/read.php?10,187809,187809#msg-187809 Edda GENERAL HEALTH FORUM Thu, 20 Oct 2022 17:21:14 +0000