Joe,
That was a very interesting link from Cleveland Clinic. It makes sense to me that phosphorous could very well be a problem for both vagal and adrenergics. My episodes were mostly brought on by the extra output of energy, whether it be walking up a hill, playing golf, or digestion, however I have also gone out of rhythm by consuming free glutamate, which takes extra ATP's per Joe South's article posted a while back, to try to eliminate the excess. In a previous post to Mike, I mentioned that our heart is like a flickering light bulb that isn't quite getting enough power. I know that's a simplistic point of view, but phosphorous is luminescent, like a light bulb, and at least most of the processes in the body are phosphorylated.
Another thing in my posted link I found interesting was this:
Cr is derived from glycine and arginine by the formation of guanidinoacetate and ornithine in a reaction catalyzed by arginine:glycine amidino-transferase (AGAT) (Walker, 1979; Wyss and Kaddurah-Daouk, 2000).
I think the glycine in the Mg is helping people in the formation of creatine. In my case, I wasn't low intracelluarly in Mg, but I was low in glycine in serum. I think I will concentrate on glycine and creatine for a while, and see what I find.
I didn't use to be a big pop drinker, even before starting Paleo, and I don't think that's a good way for people to get their pho., because of the high content of sugar, however I find it strange that I converted on pop 3-4 times, and believe me when I say, it's hard to convert atrial flutter.
The article goes on to say:
Animal Studies. The effects of Cr on cardiac tissue have been investigated. A study by Sharov et al. (1987) showed a protective effect of PCr on cardiac tissue following ischemia. Using rabbit hearts, PCr was administered intravenously either before and during cardiac artery ligation or 30 min post-ligation. These investigators found a reduction in necrotic zone under both PCr treatments compared with controls (Fig. 4). Ruda et al. (1988) found that PCr administration reduced ventricular arrhythmia after acute myocardial infarctions, but the effects of Cr on cardiac tissue are still unclear. Other studies have also shown PCr to possess anti-arrhythmic activities (Rosenshtraukh et al., 1988). Feeding Cr to healthy rats or rats after a myocardial infarction failed to increase intramuscular Cr (Horn et al., 1998). The b-blocker bispropolol has been shown to increase total cardiac Cr up to 40% (Laser et al., 1996). The ability to increase Cr and related energetics in heart tissue may be one beneficial mechanism of the action of b-blocker therapy (Laser et al., 1996). Ingwall et al. (1985) have also shown that diseased myocardium has lower Cr content. Supplementation with Cr has also provided protection to cardiac tissue from metabolic stress (Constantin-Teodosiu et al., 1995)
This is where I get confused, because when taking beta blockers, I became extremely fatigued, and my heart was fighting constantly to stay in rhythm. I wasn't taking bispropolol, however, only toprol, so I wonder what the difference is. I'll do a search and see what I find.
Thank you for finding that link, Joe. By the way, my daughter's party was a success, and she had a wonderful time. My day didn't go so well, because I went out of rhythm. I was exerting a lot more energy helping get things ready. Hmmm??? I converted using extra flec, but it took a while. I'm now reassessing my supplementing regimen, esp. in light of these articles and Kjell provoking thoughts on my craziness. Thanks Kjell, if you're reading and I hope you are. I'm only going to concentrate on what I know I was low in, which was B12, folate, molybdenum, C because I know how important that is daily, E, a few other necessary nutrients, and phosphorous and/or glycine. I'm concentrating today, on my changes, more in depth. Had I stayed in rhythm, this wouldn't have been an issue.
Richard