Awareness Alert: Non-thermal EMF Radiation Exposure and Atrial Fibrillation Part 2

b]2. 5G: Great risk for EU, U.S. and International Health! Compelling Evidence for Eight Distinct Types of Great Harm Caused by Electromagnetic Field (EMF) Exposures and the Mechanism that Cause Them - May 17, 2018[/b]
Written and Compiled by Martin L. Pall, PhD Professor Emeritus of Biochemistry and Basic Medical Sciences Washington State University Portland OR
(90 pages – pdf file) [peaceinspace.blogs.com]

(Report review by Environmental Health Trust ) This 90-page document is probably the best summary of the current available science on EMFs, backed with a very strong argument describing the mechanisms of harm, biophysics, and why 5G is a very bad idea.

Following is Pall’s summary-overview confirming eight types of harm followed by relevant excerpts from Chapters 6 and 7. This is a very informative ‘must read’ report in its entirety.

Summary:
We know that there is a massive literature, providing a high level of scientific certainty, for each of eight pathophysiological effects caused by non-thermal microwave frequency EMF exposures. This is shown in from 12 to 35 reviews on each specific effect, with each review listed in Chapter 1, providing a substantial body of evidence on the existence of each effect. Such EMFs:

1. Attack our nervous systems including our brains leading to widespread neurological/neuropsychiatric effects and possibly many other effects. This nervous system attack is of great concern.
2. Attack our endocrine (that is hormonal) systems. In this context, the main things that make us functionally different from single celled creatures are our nervous system and our endocrine systems – even a simple planaria worm needs both of these. Thus the consequences of the disruption of these two regulatory systems is immense, such that it is a travesty to ignore these findings.
3. Produce oxidative stress and free radical damage, which have central roles in essentially all chronic diseases.
4. Attack the DNA of our cells, producing single strand and double strand breaks in cellular DNA and oxidized bases in our cellular DNA. These in turn produce cancer and also mutations in germ line cells which produce mutations in future generations.
5. Produce elevated levels of apoptosis (programmed cell death), events especially important in causing both neurodegenerative diseases and infertility.
6. Lower male and female fertility, lower sex hormones, lower libido and increased levels of spontaneous abortion and, as already stated, attack the DNA in sperm cells.
7. Produce excessive intracellular calcium [Ca2+]i and excessive calcium signaling.
8. Attack the cells of our bodies to cause cancer. Such attacks are thought to act via 15 different mechanisms during cancer causation.

Relevant Excerpts:

There is also a substantial literature showing that EMFs also cause other effects including life threatening cardiac effects (Chapter 3). In addition, substantial evidence suggests EMF causation of very early onset dementias, including Alzheimer’s, digital and other types of dementias (Chapter 3); and there is evidence that EMF exposures in utero and shortly after birth can cause ADHD and autism (Chapter 5).

Each is produced via the main mechanism of action of microwave/lower frequency EMFs, activation of voltage-gated calcium channels (VGCCs) (Chapter 2). Each is produced via what are called downstream effects of VGCC activation. It follows from this that we have a good understanding not only that these effects occur, but also how they can occur. The extraordinary sensitivity of the VGCC voltage sensor to the forces of the EMFs tells us that the current safety guidelines allow us to be exposed to EMF levels that are something like 7.2 million times too high. That sensitivity is predicted by the physics.

Therefore, the physics and the biology are each pointing to the same mechanism of action of non-thermal EMFs.

Clips from Chapters 6 and 7 - how it all fits together…
Summary Chapter 6: The U.S. Early Role in Recognizing Non-Thermal EMF Effects and How This Was Abandoned Starting in 1986: U.S. Failure to Research Health Impacts of Cell Phone Towers, Cell Phones, Wi-Fi, Smart Meters and Now 5G.

What Is the Current Position of U.S. Government Agencies? pp. 58-78

In the areas discussed in Chapter 6, what used to be the primacy of U.S. science has completely disintegrated. It has disintegrated because of the cessation of U.S .government funding for either experimental studies or epidemiological studies. It has disintegrated due to attacks on U.S. and International scientists; attacks that started in the U.S. with the attacks on Dr. Henry Lai. It has disintegrated because of aggressive industry propaganda, propaganda that has no connection with the real science. It has disintegrated because of the outright corruption of the committee to set standards for radio-frequency exposures and the FCC and the possible and de facto corruption of the FDA. The telecommunications industry has been aware of much of the problems with their approach since the 1999 letter to them from George Carlo, PhD, public health scientist.

The FCC has been aware of much more of the science since my presentation to them in September 2016. The FDA has been aware of contrary findings since 1993. Each of them has, if anything, doubled down on their fictions since those respective times. Many of these things are going on internationally; however the U.S. has often been leading the world in these processes.

All of the actions we have seen to corrupt the science and public understanding of the science have the effect of making it vastly more difficult for individuals impacted by the EMFs to protect themselves from further harm. We have many effects that are cumulative and become irreversible as they become more severe, effects that impact at a minimum, tens of millions of Americans and hundreds of millions of people elsewhere in the world. Industrial and regulatory organizations make it difficult or impossible for people to have scientifically valid information also make it difficult or impossible for people to protect themselves from the accumulation of these effects, leading to severe irreversible effects.

Each of the organizations involved, both U.S. and international that collaborate in this process, have important responsibility for the consequences. I think damage goes way beyond tens and hundreds of millions of people, because I think we are looking at cumulative severe impact on our brain function, on our reproductive function and on our DNA, and that these, in turn will lead to the crash of every single technologically advanced country on earth, barring a major change in course. That will happen fairly quickly, in my opinion, even without 5G but 5G will greatly speed up the process and perhaps even add new egregious effects.

(Be sure to note the four types of blindness resulting from downstream effects of VGCC activation – Paul says: Each of the four types of blindness, have downstream effects of VGCC activation as causal factors: cataracts, detached retinas, glaucoma and macular degeneration. The aqueous and vitreous humors in the eye may be an ideal environment for the regeneration of the electrical fields within the eye. We may, therefore have a gigantic epidemic of each of the four types of blindness.)


Chapter 7: The Great Risks of 5G: What We Know and What We Don’t Know

We have already discussed two issues that are essential to understanding 5G. One is that pulsed EMFs are, in most cases, much more biologically active than are non-pulsed (often called continuous wave) EMFs.

A second is that the EMFs act by putting forces on the voltage sensor of the VGCCs, opening these calcium channels and allowing excessive calcium ions to flow into the cell. The voltage sensor is extraordinarily sensitive to those electrical forces, such that the safety guidelines are allowing us to be exposed to EMFs that are something like 7.2 million times too high.

The reason that the industry has decided to go to the extremely high frequencies of 5G is that with such extremely high frequencies, it is possible to carry much more information via much more pulsation than it is possible to carry with lower frequencies even in the microwave range. We can be assured, therefore, that 5G will involve vastly more pulsation than do EMFs that we are currently exposed to.

It follows from that, that any biological safety test of 5G must use the very rapid pulsations including whatever very short term spikes may be present, that are to be present in genuine 5G. There is an additional process that is planned to be used in 5G: phased arrays (https://en.wikipedia.org/wiki/Phased_array)

Because such forces are the way in which EMFs activate the VGCCs, it seems highly likely, therefore, that 5G radiation will be particularly active in VGCC activation.

In summary, then, 5G is predicted to be particularly dangerous for each of four different reasons:
1. The extraordinarily high numbers of antennae that are planned.
2. The very high energy outputs which will be used to ensure penetration.
3. The extraordinarily high pulsation levels.
4. The apparent high level interactions of the 5G frequency on charged groups presumably including the voltage sensor charged groups.

Also: Because the voltage sensor is so stunningly sensitive to electrical forces and part of the reason for that is the very high level of amplification of the electrical field across the plasma membrane, we have an almost perfect way in which to produce EMF effects deeply within our bodies. I am very concerned that 5G will produce very large increases in kidney failure. (continue reading at the site)

Pall statement about testing:
“The only way to do 5G safety testing is to do genuine 5G biological safety testing. I have published on how this can be done relatively easily at relatively low cost and as you saw in Chapt. 6, told the FCC how this can be done. Those tests must be done by organizations completely independent of industry and that leaves out both ICNIRP and SCENIHR and a lot of other organizations…”

The question now is what about 5G? We have with 5G strong suspicions of similar or much more severe risk of effects documented elsewhere in this document. We have no biological safety testing of genuine 5G radiation. Therefore, we have no risk analysis or risk management because we have no risk assessment whatsoever on 5G. So here we have Dr. Vinciūnas arguing that the request for precautionary principle application is premature. But it is not the request for the use of the precautionary principle that is premature, it is the Commission’s claim that it has done the required risk analysis and risk assessment.

This is the bizarre world that we live in. The European Commission has done nothing to protect European citizens from the very serious health hazards and the U.S. FDA,EPA and National Cancer Institute have done nothing to protect U.S. citizens.

The U.S. FCC has been worse than that, acting in wanton disregard for our health. Let me close, as follows. There have been certain points in our history where people have stood up to strong destructive forces against what often appeared to be insurmountable odds. Those people are THE most honored people in our history. The people who failed to do so are among the most despised people in our history.

I am not at all sure we will have historians to record us 100 years from now or even 30 years from now, given the direction in which we are heading. But if we do, rest assured that these are the standards by which we will all be judged.
Continue: [peaceinspace.blogs.com]

(My comment: A recent newspaper announcement/paid advertisement by AT&T ( 2-page spread) with graphics and large print announced testing of 5G technology in health-care/hospital settings, stadiums and the future plans for 5G service across the US listing dates of announcement headlines that began in 12/18/18 to this one dated 4/2/19.)

3. Pall: Scientific evidence contradicts findings and assumptions of Canadian Safety Panel 6: Microwaves act through voltage-gated calcium channel activation to induce biological impacts at non-thermal levels, supporting a paradigm shift for microwave/lower frequency electromagnetic field action
Martin L. Pall, Rev Environ Health 2015; 30(2) :99-136
[www.degruyter.com] Pdf download.
Definitely worth reading… as it offers important rebuttal statements in the summary observations starting on page 109 of the De Gruyter 2015 study reprint.

4. Microwave electromagnetic fields act by activating voltage-gated calcium channels: why the current international safety standards do not predict biological hazard (2014) Martin L Pall. Recent Res Devel. Mol. Cell Biol. (7(2014):0-99 ISBN:978-81-208-0000-0 [electricalpollution.com]

Abstract:
Microwave and other low frequency electromagnetic fields (EMFs) have been shown to act by activating voltage-gated calcium channels (VGCCs)with most biological effects being due to elevated intracellular calcium, consequent nitric oxide (NO) elevation and either peroxynitrite or NO signaling. This, the role of excessive intracellular calcium in microwave effects and some 20,000 papers on microwave biological effects show that the current international safety standards do not predict biological hazard. Such standards are based on the false assumption that the predominant effects of microwave and other low frequency EMF exposures are due to heating. A whole series of biological changes reportedly produced by microwave exposures can now be explained in terms of this new paradigm of EMF action via VGCC activation, including: oxidative stress; single and double stranded breaks in cellular DNA; therapeutic effects; blood-brain barrier breakdown; greatly depressed melatonin levels and sleep disruption; cancer; male and female infertility; immune dysfunction; neurological dysfunction; cardiac dysfunction including tachycardia, arrhythmia and sudden cardiac death. A two-phase program for greatly
improving EMF safety standards is proposed.
Note: The entire study is noteworthy, but check these clips from page 7

… “Most of the hormones of the body are released under the control of mechanisms triggered by VGCC activation (29). What effects there may be of such possible linkage between EMFs and hormonal control is difficult to fathom. One hormone release system that has been studied in this context is the release of epinephrine/norepinephrine from the chromaffin cells of the adrenal gland. It has been shown in two studies that EMFs stimulate the release of these two hormones by chromaffin cells by a VGCC-dependent mechanism (7) as well as in many other EMF chromaffin cell studies where a VGCC role was not tested. These two hormones, when elevated, produce major stress on the body, including psychological stress.

Another cell type where VGCCs have major roles are the pacemaker cells of the heart, endocrine system and central nervous system (29). These pacemaker cells have very high densities of VGCCs in them and may, therefore, be particularly susceptible to EMF activation. In the heart, hyperactivity of the VGCCs produces tachycardia and arrhythmias, leading in some cases to sudden cardiac death (49,50). There are studies, in two cases going back to the 1960s (51,52), showing that isolated animal hearts exposed to microwave EMFs (again, well within current safety standards) developed tachycardia and arrhythmia and Havas has shown that some electromagnetic hypersensitive (EHS) individuals developed instantaneous tachycardia when unknowingly exposed to an activated cordless phone (53,54).

We currently have an epidemic of tachycardia, arrhythmia and sudden cardiac death despite the fact that ischemic heart disease is decreasing. Could this be due to microwave EMF exposure? This is a possibility that cannot be ruled out at this point.

We are still in the early stages of studying many of these issues but safety standards should, of course, be genuinely tied to real safety, not simply to incomplete knowledge of extremely important potential and plausible hazards.

Are we going to jettison our false safety standards in favor of some that are at least somewhat biologically relevant? ” (end quotes).

5. Wi-Fi is an important threat to human health (2018)
Martin L. Pall Environmental Research Volume 164, July 2018, Pages 405-416
[reader.elsevier.com]

“ This paper is not focused on anecdotal reports but rather on 23 controlled, scientific studies of such health-related effects in animals, cells including human cells in culture and in human beings (Table 1).”

Abstract
Repeated Wi-Fi studies show that Wi-Fi causes oxidative stress, sperm/testicular damage, neuropsychiatric effects including EEG changes, apoptosis, cellular DNA damage, endocrine changes, and calcium overload. Each of these effects are also caused by exposures to other microwave frequency EMFs, with each such effect being documented in from 10 to 16 reviews.

Therefore, each of these seven EMF effects are established effects of Wi-Fi and of other microwave frequency EMFs. Each of these seven is also produced by downstream effects of the main action of such EMFs, voltage-gated calcium channel (VGCC) activation.

While VGCC activation via EMF interaction with the VGCC voltage sensor seems to be the predominant mechanism of action of EMFs, other mechanisms appear to have minor roles. (continue at the URL).

In conclusion, there are seven repeatedly-found Wi-Fi effects which have also been shown to be caused by other similar EMF exposures. Each of the seven should be considered, therefore, as established effects of Wi-Fi.

Excerpts from p. 2: Despite all of these clear and important, non-thermal effects, and the fact that there was substantial evidence for many of them already known before 1973, our current U.S. and international safety guidelines are still based on considering only thermal effects.

Mutation accumulation produced by cellular DNA damage is likely to be both cumulative and irreversible, as well, because later mutations are highly unlikely to reverse previously occurring mutations. We have therefore reason to think that such effects as brain damage to animal brains, neuropsychiatric effects in humans, reproductive dysfunction in mice and mutational effects, are each cumulative. Those same effects may be completely or largely irreversible.

One thing that this should tell us is that the short-term Wi-Fi studies shown in Table 1 may greatly underestimate the damage Wi-Fi may do over much longer time periods. Given the fact that Wi-Fi has been placed in most schools, hotels, restaurants, coffee shops, commercial aircraft and airports as well as in many homes and that Wi-Fi hot spots are becoming increase- ingly common in cities around the world, we should expect massive cumulative Wi-Fi effects in many people.

A second, tentative inference is that false assurances of safety on the part of industry are likely to lead to much more severe effects on people exposed to Wi-Fi or other EMFs; rather than leading them to protect themselves or their children by avoiding exposures or demanding that others stop non-voluntary exposures, they are likely to avoid protective changes or be prevented from doing such protective changes.

A third inference is that these effects may be among the more difficult ones for us to attribute to EMF exposure. We are much more aware of effects that occur rapidly than those that take months or years before they become readily apparent. [www.sciencedirect.com]


6. List of 155 Reviews on Non-thermal Effects of Microwave/Intermediate Frequency EMFs by Martin L. Pall 11/12/2017 [electromagnetichealth.org]


7. Electromagnetic fields act via activation of voltage-gated calcium channels to produce beneficial or adverse effect
Martin L. Pall, Professor Emeritus of Biochemistry and Basic Medical Sciences, Washington State University, Portland, OR, USA Received: January 8, 2013; Accepted: May 20, 2013 [onlinelibrary.wiley.com]

8. Electromagnetic Field Exposures Act via Voltage Regulated Calcium Channels. How this leads to diverse impacts on health.
Martin Pall, PhD (March 2016) in Stockholm, Sweden) [www.youtube.com]
Similar: Martin Pall, Ph.D.: Electromagnetic Field Exposure - The Cellular Effect on Humans YouTube 1 hr 15 min. [www.youtube.com]

9. How to Approach the Challenge of Minimizing Non-Thermal Health Effects of Microwave Radiation from Electrical Devices
Pall, Martin. ( October 2015). International Journal of Innovative Research in Engineering & Management (IJIREM). ISSN. 2350-557.
[www.emfanalysis.com]

Dozens of reviews and thousands of primary literature studies have shown the existence of many different non-thermal health effects of microwave and lower frequency electromagnetic fields (EMFs); however current safety guidelines and standards only recognize thermal effects. This leaves both individuals and companies unprotected, particularly with the very large increases in microwave frequency exposures that are occurring over time. It has recently been shown that many, perhaps even all non-thermal health effects are produced by activation of voltage-gated calcium channels (VGCCs) in the plasma membranes of cells, with EMFs activating these channels, producing large increases in intracellular calcium levels [Ca2+]i. The voltage sensor controlling the VGCCs is thought to be extremely sensitive to activation by weak EMFs. Diverse health effects are thought to be produced by downstream effects of increased [Ca2+]i produced by VGCC activation.

It is difficult if not impossible to currently predict the biological effects of different EMFs because pulsation patterns, frequencies and EMF polarization each have strong influences on biological effects; there are also windows of exposure producing maximum biological effects within the exposure window.

While decreasing exposures on the order of 100 to 1000-fold will no doubt be useful, we also need to have genuine biological measures of damage to allow optimization of both the type of EMF exposures as well as intensities. Biological optimization should be done by studying cells in culture that have high densities of various types of VGCCs, measuring such effects as increases in [Ca2+]i and increases in nitric oxide (NO) production following EMF exposures. Such cell culture-based assessment of biological damage should allow progressive improvement of wireless communication devices and various other electronic devices by choosing designs that lower biological responses.

10. Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health- promoting factors. Pall, Martin & Levine, Stephen. (2015). [www.ncbi.nlm.nih.gov]

Dr. Pall indicates that by raising the level of Nrf2 (nuclear factor-like2), a biologic hermetic that up-regulates superoxide dismutase, catalase and all the other beneficial intercellular antioxidants which lowers inflammation and improves mitochondrial function, detoxifies the body, stimulates autophagy, removes toxic protein aggregates and dysfunctional organelles and can help lower the damage from EMF exposure through the Nrf2 pathway with specific foods – details in this referenced report.

11. Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression
Martin L.Pall [doi.org].2015.08.001Get rights and content

18 more recent epidemiological studies, provide substantial evidence that microwave EMFs from cell/mobile phone base stations, excessive cell/mobile phone usage and from wireless smart meters can each produce similar patterns of neuropsychiatric effects, with several of these studies showing clear dose–response relationships.
Among the more commonly reported changes are sleep disturbance/insomnia, headache, depression/depressive symptoms, fatigue/tiredness, dysesthesia, concentration/attention dysfunction, memory changes, dizziness, irritability, loss of appetite/body weight, restlessness/anxiety, nausea, skin burning/tingling/ dermographism and EEG changes.

In summary, then, the mechanism of action of microwave EMFs, the role of the VGCCs in the brain, the impact of the non-thermal EMFs on the brain, extensive epidemiological studies performed over the past 50 years, and five criteria testing for causality, all collectively showing that various non-thermal microwave EMF exposures produce diverse neuropsychiatric effects.

12. Radiation from wireless technology affects the blood, the heart, and the autonomic nervous system. Havas M. Rev Environ Health. 2013;28(2-3):75-84. doi: 10.1515/reveh-2013-0004. [www.ncbi.nlm.nih.gov]

Abstract
Exposure to electrosmog generated by electric, electronic, and wireless technology is accelerating to the point that a portion of the population is experiencing adverse reactions when they are exposed. The symptoms of electro-hypersensitivity (EHS), best described as rapid aging syndrome, experienced by adults and children resemble symptoms experienced by radar operators in the 1940s to the 1960s and are well described in the literature. An increasingly common response includes clumping (rouleau formation) of the red blood cells, heart palpitations, pain or pressure in the chest accompanied by anxiety, and an upregulation of the sympathetic nervous system coincident with a down-regulation of the parasympathetic nervous system typical of the "fight-or-flight" response. Provocation studies presented in this article demonstrate that the response to electrosmog is physiologic and not psychosomatic. Those who experience prolonged and severe EHS may develop psychologic problems as a consequence of their inability to work, their limited ability to travel in our highly technologic environment, and the social stigma that their symptoms are imagined rather than real. PMID: 24192494 DOI: 10.1515/reveh-2013-0004 [Indexed for MEDLINE]

Provocation study using heart rate variability shows microwave radiation from 2.4 GHz cordless phone affects autonomic nervous system.
Havas M, Marrongelle J, Pollmer, Kelley E, Rees C, Tully S. 2010
Eur J Oncol 5:273-300. [www.researchgate.net]

13. Brussels becomes Brussels Becomes First Major City to Halt 5G Due to Health Effects April 3, 2019 [www.greenmedinfo.com]


III. Rouleaux formation

As noted in the foregoing Havas study (Ref.12), the rouleaux formation topic is another concern.
Additionally, the Winter 2014 edition of Weston A. Price Foundation’s publication, “Wise Traditions,” features several reports including:

Does Short-term Exposure to Cell Phone Radiation Affect the Blood? Effects of Smart Phones – A study that looks at what smart phones do to the blood.
[www.westonaprice.org]

(My comment) Note the photos of dark-field microscopy images showing red blood cell aggregation changes before and after EMF exposure illustrating effects compared to normal cells and the morphology that occurs after X amount of exposure times; i.e., where the misshapen cells take on a ‘rouleaux’ formation likened to a stack of coins, but they also can lose their normal, round shape and have burrs, spikes or are sickle-shaped rather than round, contributing also to clumping.

Worth noting for afibbers who are not on Rx anticoagulants and even if they are… I assume the shape would still distort with EMF exposure…. Note Figure 7 in the report: “Every RBC appears to be misshapen. Many of the cells show spikes and are echinocytes.”

Clumping is one issue and morphology is yet, another; so my concern is directed to what we might surmise from the rheology reports that indicate cell distortion and tendency for aggregation… outside of the action of anticoagulants or antiplatelet meds. This is not a new finding, but not often mentioned.

There are other RBC functions including delivery of oxygen and when the structures of the cells are distorted, the functions can be distorted as well as the complications of ‘log jams’ in blood vessels that cause vascular damage and other complications over time. (end of my comment)
[www.ncbi.nlm.nih.gov] - as just one example.