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RCT for Vitamin D & COVID Published

Posted by GeorgeN 
RCT for Vitamin D & COVID Published
September 04, 2020 02:24PM
Following on to all of PC, MD's posts on Vitamin D & COVID-19
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This one is important - a randomized, controlled trial of Vitamin D use in Spain. Now we can say that it is a cause of good outcomes, not an effect of bad ones. Although the study involved in mega-dosing on day one with still large doses for several days, the real message is likely to keep Vit D status up ahead of time. Practical advice:
"If one is maintaining 25(OH)D this high, one could mimic the maintenance dose of vitamin D used in this study by taking 7,600 IU per day upon the onset of symptoms through recovery.

If one goes into an illness with 25(OH)D below 20 ng/mL, one could quickly bring this level up using a bolus dosing approach like in the RCT. Their approach would equate to using 100,000 IU on the first day, followed by 18,000 IU per day for the next six days, then switching to the maintenance dose; or by using 30,000 IU each day for the first seven days, then switching to the maintenance dose; or by using 100,000 IU on the first day, 50,000 IU on the third day, 50,000 IU on the seventh day, and then switching to the maintenance dose."

Chris Masterjohn's analysis: [chrismasterjohnphd.com]

Actual study: "Effect of Calcifediol Treatment and best Available Therapy versus best Available Therapy on Intensive Care Unit Admission and Mortality Among Patients Hospitalized for COVID-19: A Pilot Randomized Clinical study"
Re: RCT for Vitamin D & COVID Published
September 05, 2020 03:02AM
Thank you for that George.

Great article. Can't believe it got published. Big Pharma ain't gonna like this.

Did't know that preventative/therapeutic levels could be reached so quickly.

So, for the D deficient that convert or just suspect the COVID, it's megadoses of C and D. Sounds easy, but not too confident the frightened clinicians will subscribe to that.
Re: RCT for Vitamin D & COVID Published
September 05, 2020 03:14PM
Quote
PC, MD
So, for the D deficient that convert or just suspect the COVID, it's megadoses of C and D. Sounds easy, but not too confident the frightened clinicians will subscribe to that.

Any time folks take Vitamin D, suggest taking Vitamin K2-MK7 at least 100 mcg/day.

I'd recently suggested a hispanic friend in El Paso, TX take at least 5,000 IU's of D3/day. He got back with me and said he'd met with his primary care doc who told him to take 1,000 IU's/day or 2,000 IU's every two days. Disappointing, and sad the medical community just hasn't caught on.
Re: RCT for Vitamin D & COVID Published
September 05, 2020 05:06PM
Yes, George, sad and pathetic.

Yes 100 µg of K2 (and magnesium to bowel tolerance) is well advised. The Hippocratic oath says first do no harm and that’s precisely what these doctors are doing by dissuading patients from the correct path.

Re: RCT for Vitamin D & COVID Published
September 08, 2020 08:59AM
Mainline Medicine looks like its finally catching up with the value of enough Vitamin D for Covid protection.

Today's WebMD article: <[www.webmd.com];
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