I have 2 weeks worth of 5mg Eliquis samples that I “forgot” to take during my last AF episode in 2018. I’ve already decided that either I or my wife contract COVID-19 then we will cut the pills in half and do the 2.5mg BID prophylaxis for PE. If a medical professional has a problem with it well, then, they can have a problem with it. I personally think that 2.5mg BID is virtually harmless in anyone who doesn’t have a serious contraindication like hemophilia, von Willebrand’s or the like.