Coleus Forskohlii Anybody ever heard of it?
Dig a little deeper. I just stumbled across it.
Forskolin stimulates and activates the enzyme adenylate cyclase in the heart and smooth muscle. This causes increased production of cyclic AMP (cAMP), which causes calcium channels to open and intracellular calcium concentrations to increase, resulting in increased contractility of heart muscle and relaxation of smooth muscle.3,4,5,6 cAMP is one of the most important regulators of endocrine health, brain chemistry and oxidative metabolism.
A clinical trial in patients with suboptimal heart function found intravenous forskolin significantly promoted diastolic blood pressure within a healthy range without increasing myocardial oxygen consumption;
left ventricular function also improved.13 In a similar study, intravenous forskolin given to patients with suboptimal heart function resulted in healthy vascular resistance and left ventricle contractility.
Could it be used as a Blood Thinner?
Warning
It is important to note consumers taking anticoagulant or antihypertensive medications should use Coleus with caution, as forskolin could potentiate the effects of those drugs.
Other issues with it.
Breast-feeding: There is not enough reliable information about the safety of taking coleus if you are breast-feeding. Stay on the safe side and avoid use.
Bleeding disorders: There is some evidence that coleus might increase the risk of bleeding in some people.
Heart disease: Coleus might lower blood pressure. There is some concern that coleus might interfere with treatment for heart or blood vessel diseases and could make these conditions worse. Use coleus with caution if you have a heart problem.
Low blood pressure: Coleus might lower blood pressure. If your blood pressure is already low, taking coleus might make it drop too much.
Surgery: Coleus might increase bleeding during and after surgery. Stop using coleus at least 2 weeks before a scheduled surgery.
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www.curezone.org] 7 yr old post
